PUBLICATIONS
In preparation/submitted:
[06] Transgenerational effects of Vinclozolin exposures on DNA methylation in pubertal rat Sertoli cells. (in preparation)
[05] Global DNA methylation in primordial germ cells induced by fungicide Vinclozolin: transgenerational effects of exposures. (in preparation)
[04] Bhandari, R.K., Schinke, E.N., and Skinner, M.K. Genome-wide analysis of DNA binding and transcriptional regulation by bHLH transcription factor TCF21 in the fetal testis during male sex determination. (in preparation)
[03] Bhandari, R.K., Haque, M.M., and Skinner, M.K. (2011). Genome-wide analysis of downstream targets of male sex determining factors, SRY and SOX9. (in preparation).
[02] Bhandari, R.K.*, Nakamura, M*., Paul-Prasanth, B., Kobayashi, Y., Kobayashi, T., Horiguchi, R., Shibata, Y., Sakai, F. Nakamoto, M., and Nagahama, Y. (2011). Estrogen depletion causes female-to-male sex reversal of adult gonochoristic fish (*Equally contributing first authors, submitted).
[01] Miura, S., Bhandari, R.K., Kobayashi, Y. and Nakamura, M. (2011). Estrogen favors differentiation of ovary in the ambisexual gonads of Anemone fish. (Accepted, Development, Growth, and Differentiation).
Published Research Articles:
[21] Bhandari, R.K., Clement, T., Sadler-Riggleman, I., and Skinner, M.K. (2011). Basic helix-loop-helix transcription factor Tcf21 is a downstream target of male sex determining gene Sry. PLoS One, 6(5): e19935. pp1-11.
[20] Clement, T*., Bhandari, R.K*., Riggleman, I., and Skinner, M.K. (2011). Sry directly regulates Neurotrophin-3 promoter during male sex determination and testis development (*Equally contributing first authors). Biol Reprod. 2011 Apr 20. [Epub ahead of print] PMID: 21508350.
[19] Kojima, Y. Bhandari, R.K., Kobayashi, Y. and Nakamura M. (2008). Male-to-female sex reversal of primary male wrasse with estrogen treatment. General and Comparative Endocrinology. 156:628-632.
[18] Westring, C.G., Ando, H., Kitahashi, T., Bhandari, R.K., Ueda, H., Urano, A., Dores, R.M., Sher, A.A. and Danielson, P.B. (2008). Seasonal changes in CRF-I and urotensin I transcript levels in masu salmon: Correlation with cortisol secretion during spawning. General and Comparative Endocrinology, 155: 126-140.
[17] Komatsu, T. Bhandari, R.K., Nakamura, M. (2006). Acceleration of precocious spermatogenesis in under-yearling Golden Rabbitfish (Siganus guttatus, Bloch) by GnRHa treatments. Aquaculture 257: 558-565.
[16] Alam, M.A., Bhandari, R.K. ,Kobayashi, Y., Soyano K., and Nakamura, M., (2006). Induction of sex change within two full moons during breeding season and spawning in grouper. Aquaculture 255: 532-535.
[15] Alam, M.A., Bhandari, R.K., Kobayashi, Y., Soyano, K., and Nakamura, M. (2006). Changes in androgen-producing cell size and circulating 11-ketotestosterone levels during female-to-male sex change in Honeycomb grouper (Epinephelus merra). Molecular Reproduction and Development. 73(2):206-14.
[14] Bhandari, R.K., Alam, M.A.,, Soyano K., and Nakamura, M., (2006). Induction of female-to-male sex change in the honeycomb grouper (Epinephelus merra) by 11-ketotestosterone treatments. Zoological Science 23: 65-69.
[13] Bhandari, R.K., Nakamura, M., Kobayashi, T., and Nagahama, Y. (2006). Suppression of steroidogenic enzyme expression during androgen-induced sex reversal in Nile tilapia (Oreochromis niloticus). General and Comparative Endocrinology 145: 20-24.
[12] Bhandari, R.K., Alam, M.A., Higa, M. Soyano, K., Nakamura, M. (2005). Evidence that estrogen regulates the sex change of honeycomb grouper (Epinephelus merra), a protogynous hermaphrodite fish. Journal of Experimental Zoology 330A: 497-503.
[11] Jodo, A.., Kitahashi, T., Taniyama, S., Bhandari, R.K., Ueda, H., Urano, A. and Ando, H. (2005). Seasonal variations in expression of five subtypes of gonadotropin-releasing hormone receptor genes in the brain of masu salmon from immaturity to spawning. Zoological Science 22: 1331-1338.
[10] Luo, Q., Ban, M., Ando, H., Kitahashi, T., Bhandari, R.K., McCormick, S.D. and Urano, A. (2005). Distinct effects of 4-nonylphenol and estrogen-17beta on expression of estrogen receptor a gene in smolting sockeye salmon. Comparative Biochemistry and Physiology. 140C: 123-130.
[09] Alam, M.A., Komuro, H., Bhandari, R.K. , Nakamura, S., Soyano, K., and Nakamura, M. (2005). Immunohistochemical evidence identifying the site of androgen production in the ovary of the protogynous grouper Epinephelus merra . Cell and Tissue Research 320: 323-329.
[08] Bhandari, R.K., Komuro, H., Higa, M., and Nakamura, M. (2004). Sex inversion of sexually immature honeycomb grouper (Epinephelus merra) by aromatase inhibitor. Zoological Science 21 (3): 305-310.
[07] Bhandari, R.K., Higa, M., Nakamura, S. and Nakamura, M. (2004). Aromatase inhibitor induces complete sex change in a protogynous honeycomb grouper, Epinephelus merra. Molecular Reproduction and development, 67(3): 303-307.
[06] Miura, S., Komatsu, T., Higa, M., Bhandari, R.K., Nakamura, S. and Nakamura, M. (2003). Gonadal sex differentiation in protandrous anemone fish, Amphiprion clarkii. Fish Physiology and Biochemistry 28: 165-166.
[05] Nakamura, M., Bhandari, R.K. and Higa, M. (2003). The role estrogens play in sex differentiation and sex changes of fish. Fish Physiology and Biochemistry 28: 113-117 (Review).
[04] Bhandari, R.K. Komuro, H., Nakamura, S., Higa, M., and Nakamura (2003). Gonadal restructuring and correlative steroid hormone profiles during natural sex change in protogynous honeycomb grouper, Epinephelus merra. Zoological Science 20: 1399-1404.
[03] Bhandari, R.K., Higa, M., Komuro, H., Nakamura, S. and Nakamura, M. (2003). Treatments with an aromatase inhibitor induces complete sex change in protogynous honeycomb grouper (Epinephelus merra). Fish Physiology and Biochemistry 28: 141-142.
[02] Bhandari, R.K., Taniyama, S., Kitahashi, T., Ando, H., Yamauchi, K., Zohar, Y., Ueda, H., and Urano, A. (2003). Seasonal changes of responses to gonadotropin-releasing hormone analog in expression of growth hormone/prolactin/somatolactin genes in the pituitary of masu salmon. General and Comparative Endocrinology 130: 55-63.
[01] Bhandari, R.K., Ushikoshi, I., Fukuoka, H., Koide, N., Yamauchi, K., and Ueda, H. (2002). Effects of Rhizopus extract administration on somatic growth and sexual maturation in lacustrine sockeye salmon, Oncorhynchus nerka. Fisheries Science. 68 (4): 776-782.
Book chapter
[01] Skinner, M.K., Nilsson, E.E., and Bhandari, R.K. (2010). Cell-Cell Signaling in the Testis and Ovary. In: Handbook of Cell Signaling Third Edition (Ralph A Bradshaw and Edward Dennis, Eds.) Academic Press/Elsevier Science Publishing. pp. 2663-2678.
Reviews
[02] Nakamura M. Alam, M.A., Kobayashi, Y. and Bhandari, R.K. (2007). The role of sex hormones in sex change of grouper, Epinephelus merra. Journal of Marine Science and Technology-Taiwan, Special issue 15: 23-27.
[01] Nakamura M., Kobayashi, Y., Miura, S. Alam, M.A., and Bhandari R.K. (2006). Sex change in coral reef fish. Fish Physiology and Biochemistry 31: 117-122.
